Therefore, it is required to take measures to prevent lifestyle-related diseases. In an observational study of Japanese male patients with ALD, obesity was found in 26%, diabetes in 34%, hypertension in 23%, and dyslipidemia in 23% of patients [18]. A U-shaped curve was also reported, in which the risk for type 2 diabetes was lower for small-volume drinkers than for nondrinkers, and the risk increased with increasing alcohol consumption https://ecosoberhouse.com/ [19]. Evidence for the health benefits of small amounts of alcohol consumption has remained controversial in recent years. All-cause mortality increased with increasing alcohol consumption, and only zero drinks minimized harm to overall health outcomes [20]. Thus, there is no basis for recommending small amounts of alcohol consumption to extend life expectancy, and the most important management of ALD is abstinence from alcohol.

Another contributing factor to the risk of ALD is high hepatic iron levels, which has been identified as a predictor of mortality in patients with alcoholic cirrhosis [112]. Iron overload is an independent factor in hepatocellular carcinoma progression [110]. High dietary iron intake may also increase the risk of hepatocellular carcinoma, suggesting that high iron intake may promote tumorigenesis [111].

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S-adenosylhomocysteine (SAH) is a product and inhibitor of methyltransferase reaction (MTs) as well as a substrate for the bidirectional enzyme SAH hydrolase (SAHH), which creates homocysteine or SAH when SAH is in excess. Hcy is metabolized by cystathionine beta-synthase (CBS) and cystathionase to produce cysteine and glutathione (GSH) in transsulfuration processes. It is also important to note that SAM inhibits MTHFR while promoting CBS expression. As a result, a SAM shortage boosts 5-Methyl THF production while lowering 5,10-Methyl THF and GSH production.

Supplementation with trace elements, including zinc, should also be considered. When anemia is observed, supplementation with iron and folic acid should also be considered. Deficiencies in vitamins and trace elements commonly found in ALD often cause irreversible damage and should always be considered in ALD treatment. Supplementation is necessary when these deficiencies are suspected.

Possible Mechanisms of Action for Vitamins

Approximately half of ALD patients have hepatic iron overload, with elevated serum ferritin levels and early transferrin saturation. Low hepcidin levels, along with iron deposition in macrophages, are usually present in these patients [147]. This results in accelerated pathological progression to cirrhosis and increased predisposition to hepatocellular carcinoma [148]. In addition to phlebotomy and iron chelation, attempts are being made to improve fibrosis by regulating iron-related proteins; however, this is still in the research stage [112].

Deficiencies in vitamin C can cause symptoms that include irritability, weakness and muscle fatigue. The best source of vitamin C in the United States is orange juice from frozen concentrate (more of the vitamin is preserved when the oranges are frozen). Alcohol-induced liver damage, extracellular matrix changes, and inflammation have all been linked to acetaldehyde [26,27]. Its actions are triggered by the formation of ROS and a redox imbalance (NAD/NADH). Consult your healthcare provider if your drinking can compromise the medication or supplements you’re currently taking and vice-versa. If you’re having issues with your drinking habits, don’t hesitate to seek out treatment options to help you stay sober.

Other Beneficial Supplements for Drinkers

In the presence of glucose intolerance or obesity, caloric requirements may be lower and require individualized attention. If oral intake is difficult, enteral nutrition should be preferred. Intravenous nutrition best vitamins for recovering alcoholics is considered the last choice because of the possibility of an infection. Vitamin C helps to keep the skin healthy, and plays an equally important role in the health of bones, teeth and blood vessels.

• To stay in recovery and live a healthier, happier life, you need to try other things.
• Alcoholism may affect the absorption, storage, metabolism, and activation of these vitamins [87].
• It has been shown that the level of selenium is lower in the group of patients with alcoholic liver cirrhosis compared to healthy ones, and it decreases proportionally with the degree of liver fibrosis [42].

If you don’t feel hungry, think about taking nutritional supplements. There’s no way around it—when you drink heavily for a long period, your body takes a hit. Overcoming alcohol use disorder can be a long and difficult process, and different people have different needs. But one often-overlooked aspect of beating addiction is nutrition in recovery.

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